Research
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Immunity:Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design
2023-06-30 -
Prof. Jiahuai Han's group reports ribosome-rescuer PELO catalyzes the oligomeric assembly and activation of NLR family proteins
2023-06-06 -
Fei-Long Meng’s group and Leng-Siew Yeap’s group shows how DNA flexibility shapes antibody gene hypermutation
2023-05-30 -
The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome
2023-05-06 -
Zhu Ping's team revealed a new mechanism of HLA-restricted autoimmune response induced by modified neoantigens in a published article in Science
2023-04-07 -
Prof. Zhengfan Jiang’s group reports that ARMH3 bridges STING and PI4KB to generate PI4P for STING transportation and activation
2023-03-31 -
Xin Wang’s team identified noncanonical role of β2-microglobulin in cognitive disorders
2023-03-31 -
Lai Ren's team revealed that lipopolysaccharide/endotoxin-binding protein is an important factor in the inhibition of monoamine synthesis and the development of depression
2023-03-30 -
Prof. Linqi Zhang and Zheng Zhang et al revealed the molecular mechanism of broadly neutralizing antibodies elicited by wild-type SARS-CoV-2 infection
2023-03-24 -
Influenza trains alveolar macrophages to fight cancer
2023-03-14 -
Prof. Dong-Ming Kuang’s team reported immunotherapy-elicited sialylation of IgG suppresses antitumorigenic type I IFN response in liver cancer
2023-02-21 -
Dr. Jie Zhou and Dr. Heping Xu’s groups identify Dopamine as negative regulator of type 2 innate lymphoid cells in allergic asthma
2023-02-20